Variational AI will participate in Discovery on Target (DOT) 2026, a leading conference dedicated to the latest advances in drug targets and enabling technologies for therapeutic discovery.
Held annually in Boston, Discovery on Target brings together scientists from pharma, biotech, and academia to explore emerging approaches for identifying and validating novel drug targets, as well as technologies that accelerate the development of new therapeutics.
Advancing the Next Generation of Drug Targets
The conference highlights cutting-edge research across a wide range of therapeutic modalities and technologies, including small molecules, biologics, and next-generation drug discovery platforms. Discussions focus on target identification, validation strategies, and emerging technologies that enable the discovery of innovative therapeutic agents.
With multiple parallel tracks, workshops, and networking opportunities, Discovery on Target provides a platform for researchers and technology innovators to exchange ideas and build collaborations across the drug discovery ecosystem.
Poster presentation
Pete will be presenting the poster C099: Initial Efforts to Discover Novel PRMT6 Inhibitors via AI-Driven Design and Synthesis, describing how Enki™ AI-guided drug design within the Enamine REAL Space enabled the rapid identification of a novel class of allosteric PRMT6 inhibitors. The new lead series has the potential for further optimization to identify a potential therapeutic treatment for spinal bulbar muscular atrophy, a rare disease under investigation by Agora Open Science Trust and Structural Genomics Consortium.
Meet with Variational AI at the event

Peter (Pete) Guzzo, EVP of Drug Discovery

Valentin Beuchillot, Director BD & Marketing
If you are attending the conference and would like to learn more about our generative molecular design platform, we would welcome the opportunity to meet.