Founded in 2019, Variational AI is pioneering a new era of small molecule drug discovery by leveraging a powerful new form of machine learning known as generative AI. Our mission is to redefine the unit economics of drug discovery, enabling biopharma partners to bring novel therapeutics to patients faster and more cost-effectively.
From oncology to other high-need therapeutic areas, we are working hand-in-hand with industry partners to unlock new chemical space and accelerate the path to novel therapies.
We are a cross-disciplinary team of machine learning researchers, computational chemists, and biotech professionals working at the intersection of AI and early drug discovery.

Handol Kim
Co-Founder & CEO

Jason Rolfe, PhD
Co-Founder & CTO

Ali Saberali, PhD
Co-Founder & Head of Platform

Peter Guzzo, PhD
EVP, Head of Drug Discovery

Roslynn Drewitt-Lange
VP, Finance & Operations

Ahmad Issa, PhD
Senior Machine Learning Scientist

Marshall Drew-Brook
Principal Machine Learning Engineer

Sara Ibrahim Omar, PhD
Computational Chemist

Alex Perryman, PhD
Principal Scientist

Brian Atwood, PhD
Scientific Project Manager

Matthew Quenneville, PhD
Machine Learning Scientist

James McSally, PhD
Computational Chemist

Yizhou Zhang, PhD
Machine Learning Scientist

Jérôme Rony, PhD
Machine Learning Scientist

Andrew Stirn, PhD
Machine Learning Scientist

Valentin Beuchillot
Senior Manager BD & Marketing

Nathania Takyi, MSc
Chemistry Data Analyst

Frank Chang
Managing Partner, Flying Fish Partner

Handol Kim
CEO, Variational AI

Hanqing Li
Investment Director, Merck GHIF

Jason Robertson
CEO, Nimbus Synergies

Jason Rolfe, PHD
CTO, Variational AI

John Boylan, PHD
SAB Member (Cell Biology/Oncology drug discovery)

Artem Cherkasov, PHD
SAB Member (Cheminformatics)

Alexander Tropsha, PHD
SAB Member (Cheminformatics)

Robert N. Young, PHD
SAB Member (Medicinal Chemistry)

Todd Farrell
Advisor (Strategy)

Jennifer Hamilton, PHD
Advisor (Strategy/Commercial)

Nancy Harrison
Advisor (Strategy/ Commercial)
Our investors include: Nimbus Synergies, Merck Global Health Innovation Fund, Flying Fish Ventures, A&E Investments, Nepenthe Capital, and an alliance of Angel investors. This support fuels the continued development of our generative AI platform, Enki, and strengthens our ability to collaborate with biopharma partners across therapeutic areas.







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